Cancer Doctors Wield Advanced Options in Treatment for Mesothelioma, though Prognosis Remains Bleak
July 4th, 2009Doctors who specialize in cancer treatment decide what type of treatment to pursue with each patient. There are numerous options. There are no regular treatment option for malignant mesothelioma sufferers. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.
The prospects for mesothelioma patients have been grim, but doctors have recently made progress. Traditional treatments for cancer are surgery (removing the tumor and surrounding tissue), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) There are problems with all three. Traditional radiation therapy has not worked well with mesothelioma patients. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.
Surgery takes out the mesothelial cancerous tissue around the tumor. This surgery is extensive and it is not clear how much the patient benefits. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and combinations of chemotherapy agents have been tried, but without much success. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.
Many advanced techniques in cancer treatment are tried on mesothelioma patients because of its high fatality rate. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. A new drug that has shown results in improving survival is pemetrexed (brand name Alimta).
Considered by oncologists is where the tumor is located, what stage the mesothelioma is in, and the age and health of the patient. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Patients afflicted with mesothelioma are benefitting in these clinical trials.
Posted in 